In order to detect, identify and quantify seven parabens present in each of the three skin layers namely Stratum Corneum, Epidermis, and Dermis (sourced from leave-on cosmetics), researchers have developed a new method which is claimed to have potential to detect paraben content from 0.026 to 0.090 μg mL−1. The proposed method is expected to help assess paraben’s skin bioaccumulation since people are repeatedly exposed to consumer goods containing parabens in their daily routine, posing a chronic risk to human health.