Anti-Pollution Activity, Antioxidant and Anti-Inflammatory Effects of Fermented Extract from Smilax china Leaf in Macrophages and Keratinocytes

In this study, according to the generalized protocol available to objectively substantiate the ‘anti-pollution’ claim, scientists evaluated several biomarkers after pollutants exposure in Raw 264.7 macro-phages and HaCaT keratinocytes to investigate the possibility of anti-pollution cosmetic material of fermented extract from Smilax china leaves (FESCL). FESCL decreased pollutants-induced luciferase activity in a dose-dependent manner, and FESCL significantly inhibited XRE-luciferase activity at a concentration of 1%. Results confirm the anti-pollution activity of FESCL against the pollutant-stimulated human living skin explants and endorse FESCL to be used as one of the functional materials in cosmetic formulation.