An Open-Label Clinical Trial Analyzing the Efficacy of a Novel Telomere-Protecting Antiaging Face Cream

News Date
September 9, 2022

While investigating the effect of a cycloartane-type triterpene glycoside astragaloside IV, which is one of the primary compounds from the aqueous extract of Astragalus membranaceus that provides telomere protection both in vitro and in vivo, as a part of antiaging skincare solution development strategy, telomere length in human skin samples was analyzed after daily treatment for 4 weeks. Results showed that the product improved hydration by 95%, the skin appeared brighter by 90%, and wrinkle visibility was reduced by 70%. The combination of biologically active compounds in the cream was claimed to possess telomere-protecting properties and notable antioxidant activity in vitro and in vivo.

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